Paper details: Please write a systematic review research paper about the actual state of the art / actual state of research. The paper should have the sections abstract, introduction, material and methods, results, discussion and conclusion. Please use the Vancouver Citation Style System for the citations. The research paper needs 70 actual references from the last 10 years (2007-2017). Therefore a systematic literature search needs to be done using PubMed and other sources. Mainly a comparision and discussion of the results found is interesting. The abstract should also be a structured abstract with the same sections background, aim, material and methods, results, discussion and conclusion.